The cold case: Are rhinoviruses perfectly adapted pathogens?

Rhinoviruses, which cause common cold, belong to the Picornaviridae family, small non-enveloped viruses (diameter 15-30 nm) containing a single-stranded RNA genome (about 7 kb). Over 100 different rhinoviral serotypes have been identified thus far, establishing rhinoviruses as the most diverse group of Picornaviridae. Based on receptor binding properties, rhinoviruses are divided into two classes: the major group binding to intracellular adhesion molecule-1 and the minor group binding to the very low density lipoprotein receptors. Interactions between virus and the receptor molecules cause a conformational change in the capsid, which is a prerequisite for viral uptake. Rhinoviruses trigger a chemokine response upon infection that may lead to exacerbation of the symptoms of common cold, i.e. asthma and inflammation. The following review aims to summarize the knowledge about rhinoviral infections and discusses therapeutical approaches against this almost perfectly adapted pathogen.     

驾驶员最优预见跟踪仿真研究

预见信息的加入能使驾驶员提前感知跟踪目标未来变化,从而对飞机做出超前控制。研究了驾驶员最优预见跟踪控制算法,理论分析得出预见信息对预见控制的作用特点。最后通过人机系统模拟实验,验证了预见信息对驾驶员超前补偿的特性。     

两种信令方式的转换及其实现

介绍了目前应用于我国长途电话交换局的两种主要的线路信令方式及其转换原理．分析了可能出现的“闭塞”现象，提出了解决方法，给出了实现方案和实际应用结果．     

计算机景观仿真技术在城市规划设计中的应用

计算机图形、图像处理技术在城市规划建筑设计中得到了广泛应用。以当前各种计算机景观仿真技术的基本原理为基础，从工作成本、设备要求、仿真效果、使用条件等方面进行了讨论、比较，为城市规划、建筑设计工作者的合理选择提供参考。     

IBM－PC机多模块宏汇编程序之间数据通信的实用方法

编写多模块汇编程序时，不同模块之间的数据通信是一个不易处理好的问题。本文通过二个实例介绍了两种简单而又实用的方法，使多模块汇编程序之间的数据通信过程大为简化，并且易于理解、掌握和使用。参３。     

基于DSP的电子耳蜗语音处理器的研制

电子耳蜗是一项正在迅速发展的聋人康复新技术，其关键是要研制出可靠、灵活、价格低廉的产品。首先介绍电子耳蜗的原理及其进展，然后介绍基于TMS320VC5402 DSP处理器的电子耳蜗语音处理器。实验证明：基于DSP的电子耳蜗系统可以按照患者的实际情况灵活选择各种语音处理方案，并能方便实现语音预处理、噪声抑制和对应各电极的频谱阈值调整，是一种比较好的系统结构。     

提高酸牛奶加工工艺及品质的研究

用保加利亚乳酚杆菌（Ｌａｃｔｏｂａｃｉｌｌｕｓｂｕｌｇａｒｉｃｕｓ）和乳酸链球菌（Ｓｔｒｅｐｔｕｃｏｃｃｕｓｔａｃｔｉｓ），按２．５：１的菌种作为发酵剂，用“正文试验”筛选配方，确定乳中干物质为１２％（±０．１％），用９５℃保温杀菌５ｍｉｎ，接种３％发酵剂，恒温条件４３℃／３ｈ，冷却到４℃３０ｍｉｎ，这些是获得风味良好酸牛奶的主要条件。在酸牛奶中主要风味物质乙醛含量达到４１．５ｐｐｍ，二乙酰含量为１６；４０ｐｐｍ，柠檬酸为１．２ｐｐｍ，达到以上所测成分，是确定酸牛奶加工工艺及提高品质的关键。     

Family I.3 lipase: bacterial lipases secreted by the type I secretion system

Based on the classification of bacterial lipolytic enzymes, family I.3 lipase is a member of the large group of Gram-negative bacterial true lipases. This lipase family is distinguished from other families not only by the amino acid sequence, but also by the secretion mechanism. Lipases of family I.3 are secreted via the well-known type I secretion system. Like most of proteins secreted via this system, family I.3 lipases are composed of two domains with distinct yet related functions. Recent years have seen an increasing amount of research on this lipase family, in terms of isolation, secretion mechanism, as well as biochemical and biophysical studies. This review describes our current knowledge on the structure-function relationships of family I.3 lipase, with an emphasis on its secretion mechanism. Received 18 April 2006; received after revision 3 July 2006; accepted 24 August 2006     

一种改进的实信号IFFT算法

由于重量轻、体积小、功耗低、功能强的小卫星工作在无人干预的低温 ,高辐射的空间环境中 ,因此星上计算机系统必须满足集成度高、寿命长、可靠性高、抗辐射能力强的要求。针对立体测绘小卫星的特点 ,我们设计了满足上述要求的集集中控制与分布控制优点于一身的星上计算机系统 ,对其可靠性进行了分析 ,并对提高其可靠性应采取的关键技术进行了简要的论述。     

铁谱磨粒数字特征分析系统

应用图像处理技术建立了铁谱磨粒数字特征分析系统，有效地解决了大量提取磨损状态信息与减少主观因素影响的矛盾。系统分为基本操作、图像预处理和特征参数３个模块。文中对系统的主要功能及算法作了介绍并给出了计算实例。